| Title | The Crystal Structure of TrpD, a Metabolic Enzyme Essential for Lung Colonization by Mycobacterium tuberculosis, in Complex with its Substrate Phosphoribosylpyrophosphate. J.Mol.Biol. 355 784-797 2006 | | Site | TBSGC | | PDB Id | | Target Id | Rv2192c | | Related PDB Ids 2bpq | | Molecular Characteristics | | Source | Mycobacterium tuberculosis h37rv | | Alias Ids | TPS20673,15609329, P66992, 15609329, P66992, NP_216708.1 | Molecular Weight | 37737.56 Da. | | Residues | 370 | Isoelectric Point | 5.99 | | Sequence | malsaegssggsrggspkaeaasvpswpqilgrltdnrdlargqaawamdqimtgnarpaqiaafavam tmkaptadevgelagvmlshahplpadtvpddavdvvgtggdgvntvnlstmaaivvaaagvpvvkhgn raasslsggadtlealgvridlgpdlvarslaevgigfcfaprfhpsyrhaaavrreigvptvfnllgp ltnparpragligcafadlaevmagvfaarrssvlvvhgddgldeltttttstiwrvaagsvdkltfdp agfgfaraqldqlaggdaqanaaavravlggargpvrdavvlnaagaivahaglssraewlpaweeglr rasaaidtgaaeqllarwvrfgrqi | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.30 | Rfree | 0.255 | | Matthews' coefficent | 2.56 | Rfactor | 0.194 | | Waters | 277 | Solvent Content | 51.90 |
| Ligand Information | | Ligands | PRP (ALPHA-PHOSPHORIBOSYLPYROPHOSPHORIC) x 1;BAM (BENZAMIDINE) x 1 | | Metals | MG (MAGNESIUM) x 2 | | |
