| Title | Structure of Mycobacterium tuberculosis PknB supports a universal activation mechanism for Ser/Thr protein kinases. Nat.Struct.Biol. 10 168-174 2003 | | Site | TBSGC | | PDB Id | | Target Id | Rv0014c | | Related PDB Ids 1o6y | | Molecular Characteristics | | Source | | | Alias Ids | TPS9414,15607156, P0A5S4, 15607156, NP_214528.1 | Molecular Weight | 66506.14 Da. | | Residues | 626 | Isoelectric Point | 5.22 | | Sequence | mttpshlsdryelgeilgfggmsevhlardlrlhrdvavkvlradlardpsfylrfrreaqnaaalnhp aivavydtgeaetpagplpyivmeyvdgvtlrdivhtegpmtpkraieviadacqalnfshqngiihrd vkpanimisatnavkvmdfgiaraiadsgnsvtqtaavigtaqylspeqargdsvdarsdvyslgcvly evltgeppftgdspvsvayqhvredpippsarheglsadldavvlkalaknpenryqtaaemradlvrv hngeppeapkvltdaertsllssaagnlsgprtdplprqdlddtdrdrsigsvgrwvavvavlavltvv vtiaintfggitrdvqvpdvrgqssadaiatlqnrgfkirtlqkpdstippdhvigtdpaantsvsagd eitvnvstgpeqreipdvstltyaeavkkltaagfgrfkqanspstpelvgkvigtnppanqtsaitnv viiivgsgpatkdipdvagqtvdvaqknlnvygftkfsqasvdsprpagevtgtnppagttvpvdsvie lqvskgnqfvmpdlsgmfwvdaeprlralgwtgmldkgadvdaggsqhnrvvyqnppagtgvnrdgiitlrfgq | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 3.00 | Rfree | 0.297 | | Matthews' coefficent | 2.61 | Rfactor | 0.232 | | Waters | | Solvent Content | 52.82 |
| Ligand Information | | Ligands | AGS (PHOSPHOTHIOPHOSPHORIC) x 2 | | Metals | MG (MAGNESIUM) x 4 | | |
