| Title | Crystal Structure of Inositol 1-Phosphate Synthase from Mycobacterium Tuberculosis, a Key Enzyme in Phosphatidylinositol Synthesis. Structure 10 393 2002 | | Site | TBSGC | | PDB Id | | Target Id | Rv0046c | | Molecular Characteristics | | Source | Mycobacterium tuberculosis h37rv | | Alias Ids | TPS27417,15607188, P71703, 15607188, NP_214560.1 | Molecular Weight | 40091.42 Da. | | Residues | 367 | Isoelectric Point | 5.02 | | Sequence | msehqslpapeastevrvaivgvgncasslvqgveyyynaddtstvpglmhvrfgpyhvrdvkfvaafd vdakkvgfdlsdaifasenntikiadvaptnvivqrgptldgigkyyadtielsdaepvdvvqalkeak vdvlvsylpvgseeadkfyaqcaidagvafvnalpvfiasdpvwakkftdarvpivgddiksqvgatit hrvlaklfedrgvqldrtmqlnvggnmdflnmlererleskkisktqavtsnlkrefktkdvhigpsdh vgwlddrkwayvrlegrafgdvplnleyklevwdspnsagviidavraakiakdrgiggpvipasaylm ksppeqlpddiaraqleefiig | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 1 | | Resolution (Å) | 1.95 | Rfree | 0.239 | | Matthews' coefficent | 2.8 | Rfactor | 0.211 | | Waters | 170 | Solvent Content | 56 |
| Ligand Information | | Ligands | NAD (NICOTINAMIDE-ADENINE-DINUCLEOTIDE) x 1;CAC (CACODYLATE) x 1 | | Metals | ZN (ZINC) x 1 | | |
