| Title | Crystal structure and function of the isoniazid target of Mycobacterium tuberculosis. Science 267 1638-1641 1995 | | Site | TBSGC | | PDB Id | | Target Id | Rv1484 | | Related PDB Ids 1eny 1bvr 1zid 1p44 1p45 2aq8 2b35 2b36 2b37 2h7i 2h7l 2h7m 2h7n 2h7p 2nv6 | | Molecular Characteristics | | Source | | | Alias Ids | TPS9457,15608622, P0A5Y6, 15608622, NP_216000.1 | Molecular Weight | 28526.21 Da. | | Residues | 269 | Isoelectric Point | 5.73 | | Sequence | mtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakaplleldvqnee hlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgihisaysyasmakallpim npggsivgmdfdpsrampaynwmtvaksalesvnrfvareagkygvrsnlvaagpirtlamsaivggal geeagaqiqlleegwdqrapigwnmkdatpvaktvcallsdwlpattgdiiyadggahtqll | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 1 | | Resolution (Å) | 2.70 | Rfree | | | Matthews' coefficent | 3.57 | Rfactor | 0.1930000 | | Waters | 48 | Solvent Content | 65.52 |
| Ligand Information | | Ligands | NAD (NICOTINAMIDE-ADENINE-DINUCLEOTIDE) x 1 | | Metals | | | |