| Title | Crystal structure of the Mycobacterium tuberculosis enoyl-ACP reductase, InhA, in complex with NAD+ and a C16 fatty acyl substrate. J.Biol.Chem. 274 15582-15589 1999 | | Site | TBSGC | | PDB Id | | Target Id | Rv1484 | | Related PDB Ids 1enz 1eny 1zid 1p44 1p45 2aq8 2b35 2b36 2b37 2h7i 2h7l 2h7m 2h7n 2h7p 2nv6 | | Molecular Characteristics | | Source | | | Alias Ids | TPS9459,15608622, P0A5Y6, 15608622, NP_216000.1 | Molecular Weight | 28526.21 Da. | | Residues | 269 | Isoelectric Point | 5.73 | | Sequence | mtglldgkrilvsgiitdssiafhiarvaqeqgaqlvltgfdrlrliqritdrlpakaplleldvqnee hlaslagrvteaigagnkldgvvhsigfmpqtgmginpffdapyadvskgihisaysyasmakallpim npggsivgmdfdpsrampaynwmtvaksalesvnrfvareagkygvrsnlvaagpirtlamsaivggal geeagaqiqlleegwdqrapigwnmkdatpvaktvcallsdwlpattgdiiyadggahtqll | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 6 | | Resolution (Å) | 2.80 | Rfree | 0.344 | | Matthews' coefficent | 2.37 | Rfactor | 0.217 | | Waters | 663 | Solvent Content | 53.00 |
| Ligand Information | | Ligands | NAD (NICOTINAMIDE-ADENINE-DINUCLEOTIDE) x 6;THT (TRANS-2-HEXADECENOYL-(N-ACETYL-CYSTEAMINE)-THIOESTER) x 4 | | Metals | | | |
