| Title | Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. Proc.Natl.Acad.Sci.Usa 103 2063-2068 2006 | | Site | NYSGXRC | | PDB Id | | Target Id | NYSGXRC-9502a | | Related PDB Ids 2b58 2b5g 2b4d 2b3v 2b4b | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | TPS7852,NP_00296, PF00583 | Molecular Weight | 20022.95 Da. | | Residues | 171 | Isoelectric Point | 5.09 | | Sequence | makfvirpataadcsdilrlikelakyeymeeqviltekdlledgfgehpfyhclvaevpkehwtpegh sivgfamyyftydpwigkllyledffvmsdyrgfgigseilknlsqvamrcrcssmhflvaewnepsin fykrrgasdlsseegwrlfkidkeyllkmatee | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 1 | | Resolution (Å) | 1.85 | Rfree | 0.24 | | Matthews' coefficent | 2.14 | Rfactor | 0.21 | | Waters | 157 | Solvent Content | 42.53 |
| Ligand Information | | Ligands | SO4 (SULFATE) x 2 | | Metals | | | |