| Title | Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis. Biochem.J. 411 351-360 2008 | | Site | TBSGC | | PDB Id | 1xxx | Target Id | Rv2753c | | Molecular Characteristics | | Source | Mycobacterium tuberculosis h37rv | | Alias Ids | | Molecular Weight | 30426.87 Da. | | Residues | 296 | Isoelectric Point | 5.45 | | Sequence | ttvgfdvaarlgtlltamvtpfsgdgsldtataarlanhlvdqgcdglvvsgttgesptttdgekiellr avleavgdrrviagagtydtahsirlakacaaegahgllvvtpyyskppqrglqahftavadatelpml lydipgrsavpiepdtiraashpnivgvkdakadlhsgaqimadtglayysgddalnlpwlamgatgfi sviahlaagqlrellsafgsgdiatarkiiavaplcnamsrlggvtlskaglrlqgidvgdprlpqvaa tpeqidalaadmraasvlr | | | BLAST FFAS ProFunc GPSS |
| Structure Determination | | Method | XRAY | Chains | 8 | | Resolution (Å) | 2.28 | Rfree | 0.215 | | Matthews' coefficent | 2.08 | Rfactor | 0.148 | | Waters | 1587 | Solvent Content | 40.32 |
| Ligand Information | | Ligands | DTT (2,3-DIHYDROXY-1,4-DITHIOBUTANE) x 8 | | Metals | MG (MAGNESIUM) x 8;CL (CHLORIDE) x 8 | | |
