| Title | The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D. Nat.Struct.Biol. 10 843-848 2003 | | Site | SPINE | | PDB Id | 1olz | Target Id | OPTIC7164 | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | Q92854, | Molecular Weight | 96144.76 Da. | | Residues | 862 | Isoelectric Point | 8.25 | | Sequence | mrmctpirgllmalavmfgtamafapipritwehrevhlvqfhepdiynysalllsedkdtlyigareav favnalnisekqhevywkvsedkkakcaekgkskqteclnyirvlqplsatslyvcgtnafqpacdhln ltsfkflgknedgkgrcpfdpahsytsvmvdgelysgtsynflgsepiisrnsshsplrteyaipwlne psfvfadvirkspdspdgeddrvyffftevsveyefvfrvlipriarvckgdqgglrtlqkkwtsflka rlicsrpdsglvfnvlrdvfvlrspglkvpvfyalftpqlnnvglsavcaynlstaeevfshgkymqst tveqshtkwvryngpvpkprpgacidsearaanytsslnlpdktlqfvkdhplmddsvtpidnrprlik kdvnytqivvdrtqaldgtvydvmfvstdrgalhkaislehavhiieetqlfqdfepvqtlllsskkgn rfvyagsnsgvvqaplafcgkhgtcedcvlardpycawspptatcvalhqtespsrgliqemsgdasvc pdkskgsyrqhffkhggtaelkcsqksnlarvfwkfqngvlkaespkyglmgrknllifnlsegdsgvy qclseervknktvfqvvakhvlevkvvpkpvvaptlsvvqtegsriatkvlvastqgsspptpavqats sgaitlppkpaptgtscepkivintvpqlhsektmylkssdnrllmslflfffvlflclffyncykgyl prqclkfrsalligkkkpksdfcdreqslketlvepgsfsqqngehpkpaldtgyeteqdtitskvptd redsqriddlsardkpfdvkcelkfadsdadgd | | | BLAST FFAS ProFunc GPSS |
| Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.00 | Rfree | 0.27 | | Matthews' coefficent | 2.89 | Rfactor | 0.206 | | Waters | 841 | Solvent Content | 57.00 |
| Ligand Information | | Ligands | | | Metals | | | |
