| Title | Crystal Structure of the Complex of Human Epidermal Growth Factor and Receptor Extracellular Domains. Cell (Cambridge,Mass.) 110 775-787 2002 | | Site | RSGI | | PDB Id | 1ivo | Target Id | srz001000016.1 | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | | Molecular Weight | 134284.21 Da. | | Residues | 1210 | Isoelectric Point | 6.31 | | Sequence | mrpsgtagaallallaalcpasraleekkvcqgtsnkltqlgtfedhflslqrmfnncevvlgnleityv qrnydlsflktiqevagyvlialntveriplenlqiirgnmyyensyalavlsnydanktglkelpmrn lqeilhgavrfsnnpalcnvesiqwrdivssdflsnmsmdfqnhlgscqkcdpscpngscwgageencq kltkiicaqqcsgrcrgkspsdcchnqcaagctgpresdclvcrkfrdeatckdtcpplmlynpttyqm dvnpegkysfgatcvkkcprnyvvtdhgscvracgadsyemeedgvrkckkcegpcrkvcngigigefk dslsinatnikhfknctsisgdlhilpvafrgdsfthtppldpqeldilktvkeitgflliqawpenrt dlhafenleiirgrtkqhgqfslavvslnitslglrslkeisdgdviisgnknlcyantinwkklfgts gqktkiisnrgensckatgqvchalcspegcwgpeprdcvscrnvsrgrecvdkckllegeprefvens eciqchpeclpqamnitctgrgpdnciqcahyidgphcvktcpagvmgenntlvwkyadaghvchlchp nctygctgpglegcptngpkipsiatgmvgalllllvvalgiglfmrrrhivrkrtlrrllqerelvep ltpsgeapnqallrilketefkkikvlgsgafgtvykglwipegekvkipvaikelreatspkankeil deayvmasvdnphvcrllgicltstvqlitqlmpfgclldyvrehkdnigsqyllnwcvqiakgmnyle drrlvhrdlaarnvlvktpqhvkitdfglakllgaeekeyhaeggkvpikwmalesilhriythqsdvw sygvtvwelmtfgskpydgipaseissilekgerlpqppictidvymimvkcwmidadsrpkfreliie fskmardpqrylviqgdermhlpsptdsnfyralmdeedmddvvdadeylipqqgffsspstsrtplls slsatsnnstvacidrnglqscpikedsflqryssdptgaltedsiddtflpvpeyinqsvpkrpagsv qnpvyhnqplnpapsrdphyqdphstavgnpeylntvqptcvnstfdspahwaqkgshqisldnpdyqq dffpkeakpngifkgstaenaeylrvapqssefiga | | | BLAST FFAS ProFunc GPSS |
| Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 3.30 | Rfree | 0.326 | | Matthews' coefficent | | Rfactor | 0.255 | | Waters | 79 | Solvent Content | |
| Ligand Information | | Ligands | NAG (N-ACETYL-D-GLUCOSAMINE) x 8;NAG-NAG (N-ACETYL-D-GLUCOSAMINE) x 1 | | Metals | | | |
