| Title | X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease. J.Biol.Chem. 280 23815-23819 2005 | | Site | ISPC | | PDB Id | 1y7v | Target Id | W00572 | | Molecular Characteristics | | Source | Carrot embrionic cell | | Alias Ids | P04062, | Molecular Weight | 55575.49 Da. | | Residues | 497 | Isoelectric Point | 7.11 | | Sequence | arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanhtgtgllltlq peqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniirvpmascdfsirtytyadtp ddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwtsptwlktngavngkgslkgqpgdiyhqt waryfvkfldayaehklqfwavtaenepsagllsgypfqclgftpehqrdfiardlgptlansthhnvr llmlddqrlllphwakvvltdpeaakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgsk fweqsvrlgswdrgmqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqp mfyhlghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfletis pgysihtylwhrq | | | BLAST FFAS ProFunc GPSS |
| Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.40 | Rfree | 0.28 | | Matthews' coefficent | 3.07 | Rfactor | 0.242 | | Waters | 286 | Solvent Content | 58.41 |
| Ligand Information | | Ligands | NAG-NAG (N-ACETYL-D-GLUCOSAMINE) x 2;SO4 (SULFATE) x 13;INS (1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE) x 2 | | Metals | | | |
