| Title | X-ray structure of human acid-beta-glucosidase, the defective enzyme in Gaucher disease. Embo Rep. 4 704-709 2003 | | Site | ISPC | | PDB Id | 1ogs | Target Id | W00186 | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | P04062, | Molecular Weight | 55575.49 Da. | | Residues | 497 | Isoelectric Point | 7.11 | | Sequence | arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanhtgtgllltlq peqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniirvpmascdfsirtytyadtp ddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwtsptwlktngavngkgslkgqpgdiyhqt waryfvkfldayaehklqfwavtaenepsagllsgypfqclgftpehqrdfiardlgptlansthhnvr llmlddqrlllphwakvvltdpeaakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgsk fweqsvrlgswdrgmqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykqp mfyhlghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfletis pgysihtylwhrq | | | BLAST FFAS ProFunc GPSS |
| Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.00 | Rfree | 0.23 | | Matthews' coefficent | 2.90 | Rfactor | 0.195 | | Waters | 939 | Solvent Content | 57.50 |
| Ligand Information | | Ligands | NAG-NAG (N-ACETYL-D-GLUCOSAMINE) x 1;NDG (2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE) x 1;SO4 (SULFATE) x 15 | | Metals | | | |
