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2fgc

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Crystal structure of Acetolactate synthase- small subunit from Thermotoga maritima. To be Published
    Site MCSG
    PDB Id 2fgc Target Id APC4257
    Molecular Characteristics
    Source Thermotoga maritima
    Alias Ids TPS4598,AAD35634, 2336 Molecular Weight 19441.67 Da.
    Residues 171 Isoelectric Point 6.77
    Sequence mtdqirehlvsmlvhnkpgvmrkvanlfarrgfnissitvgesetpglsrlvimvkgddktieqiekqa yklvevvkvtpidplpenrveremalikvrfdedkqeifqlveifrgkiidvsregaiieitgarskve afinllpqkqveeiartgivamnrwnvkegegf
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 1
    Resolution (Å) 2.30 Rfree 0.23643
    Matthews' coefficent 2.45 Rfactor 0.1680
    Waters 41 Solvent Content 49.80

    Pathway

    Reactions found in Metabolic Reconstruction for TM0549

    Name: 2-aceto-2-hydroxybutanoate synthase
    Other genes that carryout this rxn:TM0548
    Metabolic Subsystem: "Valine, Leucine, and Isoleucine Metabolism"
    Reaction: : 2obut + h + pyr --> 2ahbut + co2

     
    Name: acetolactate synthase
    Other genes that carryout this rxn:TM0548
    Metabolic Subsystem: "Valine, Leucine, and Isoleucine Metabolism"
    Reaction: : h + pyr --> alac-S + co2
    Classification: EC:4.1.3.18
     

    Ligand Information
    Ligands
    Metals MG (MAGNESIUM) x 1

    Jmol

     
    Google Scholar output for 2fgc
    1. Crystal structures of TM0549 and NE1324two orthologs of E. coli AHAS isozyme III small regulatory subunit
    JJ Petkowski, M Chruszcz, MD Zimmerman - Protein , 2007 - Wiley Online Library
     

    Protein Summary


    Ligand Summary

    Reviews

    References

     

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