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1ilv

    Table of contents
    1. 1. Protein Summary
    2. 2. Ligand Summary

    Title Structure of Thermotoga maritima stationary phase survival protein SurE: a novel acid phosphatase. Structure 9 1095-1106 2001
    Site MCSG
    PDB Id 1ilv Target Id APC175
    Molecular Characteristics
    Source Thermotoga maritima
    Alias Ids TPS4461,AAD36729, 2336 Molecular Weight 28073.59 Da.
    Residues 247 Isoelectric Point 4.99
    Sequence mrilvtnddgiqskgiivlaellseehevfvvapdkersatghsitihvplwmkkvfiservvaysttg tpadcvklaynvvmdkrvdlivsgvnrgpnmgmdilhsgtvsgamegammnipsiaissanyespdfeg aarflidflkefdfslldpftmlninvpageikgwrftrqsrrrwndyfeervspfgekyywmmgevie dddrddvdykavregyvsitpihpfltneqclkklrevyd
      BLAST   FFAS

    Structure Determination
    Method XRAY Chains 2
    Resolution (Å) 2.00 Rfree 0.258
    Matthews' coefficent 2.65 Rfactor 0.244
    Waters 252 Solvent Content 53.53

    Pathway

    Reactions found in Metabolic Reconstruction for TM1662

    Name: 5'-nucleotidase
    Other genes that carryout this rxn:TM1878
    Metabolic Subsystem: NAD Metabolism
    Reaction: : h2o + nicrnt --> nicrns + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (dTMP)
    Other genes that carryout this rxn: TM1878
    Metabolic Subsystem: NAD Metabolism
    Reaction: : h2o + nmn --> pi + rnam
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (dAMP)
    Metabolic Subsystem: Purine Metabolism
    Reaction: : damp + h2o --> dad-2 + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (AMP)
    Other genes that carryout this rxn:TM1878
    Metabolic Subsystem: Purine Metabolism
    Reaction: : amp + h2o --> adn + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (XMP)
    Other genes that carryout this rxn: TM1878
    Metabolic Subsystem: Purine Metabolism
    Reaction: : h2o + xmp --> pi + xtsn
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (IMP)
    Other genes that carryout this rxn:TM1878
    Metabolic Subsystem: Purine Metabolism
    Reaction: : h2o + imp --> ins + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (GMP)
    Other genes that carryout this rxn: TM1878
    Metabolic Subsystem: Purine Metabolism
    Reaction: : gmp + h2o --> gsn + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (dGMP)
    Metabolic Subsystem: Purine Metabolism
    Reaction: : dgmp + h2o --> dgsn + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (dCMP)
    Metabolic Subsystem: Pyrimidine Metabolism
    Reaction: : dcmp + h2o --> dcyt + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (dUMP)
    Metabolic Subsystem: Pyrimidine Metabolism
    Reaction: : dump + h2o --> duri + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (dTMP)
    Metabolic Subsystem: Pyrimidine Metabolism
    Reaction: : dtmp + h2o --> pi + thymd
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (CMP)
    Other genes that carryout this rxn: TM1878
    Metabolic Subsystem: Pyrimidine Metabolism
    Reaction: : cmp + h2o --> cytd + pi
    Classification: EC:3.1.3.5
     
    Name: 5'-nucleotidase (UMP)
    Other genes that carryout this rxn:TM1878
    Metabolic Subsystem: Pyrimidine Metabolism
    Reaction: : h2o + ump --> pi + uri
    Classification: EC:3.1.3.5
     

    Ligand Information
    Ligands
    Metals

    Jmol

     
    Google Scholar output for 1ilv
    1. Structure of Thermotoga maritima Stationary Phase Survival Protein SurE:: A Novel Acid Phosphatase
    RG Zhang, T Skarina, JE Katz, S Beasley - Structure, 2001 - Elsevier
     
    2. Structure and Function of an Archaeal Homolog of Survival Protein E (SurE [alpha]): An Acid Phosphatase with Purine Nucleotide Specificity
    C Mura, JE Katz, SG Clarke, D Eisenberg - Journal of molecular biology, 2003 - Elsevier
     
    3. Crystal structure of the stationary phase survival protein SurE with metal ion and AMP
    W Iwasaki, K Miki - Journal of molecular biology, 2007 - Elsevier
     
    4. Structure of SurE protein from Aquifex aeolicus VF5 at 1.5 A resolution
    SV Antonyuk, MJ Ellis, RW Strange - Section F: Structural , 2009 - scripts.iucr.org
     
    5. 3.7 OTHER ANTIOXIDANT ENZYMES
    VN GLADYSHEV - Redox biochemistry, 2008 - books.google.com
     

    Protein Summary


    Ligand Summary

    Reviews

    References

     

    No references found.

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