2q7x

Protein Summary

The SP_1565 gene from Streptococcus pneumoniae TIGR4 encodes for a protein, NP_346012, from the UPF0052 group (PF01933). Genome context analysis indicates a functional link (score 0.97) of SP_1565 with its genomic neighbor SP_1566, a UPF0042 nucleotide binding protein.

2q7x structure adopts a mainly helical fold and belongs to the class of LPPG:Fo 2-phospho-L-lactate transferases (SCOP CofD-like family). 2q7x has considerable structural similarity (Dali Z=20) to chain A of 3c3d [Ref], corroborated by a significant hit in HHpred. Therefore, evidence is given that this protein structure is a putative 2-phospho-(L)-lactate transferase. A structural superposition of 2q7x and 3c3d shows conservation of the GDP binding site residues. Other similar structures (Z=34-28) determined by the PSI include 2o2z, 2hzb, 2ppv, and 2p0y. See the TOPSAN PF01933 groups page for details.

Ligand Summary

References