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T. maritima Browser
1t3v
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Protein Summary
The gene TM1816 from Thermotoga maritima encodes the NP_229613 protein, a putative dinitrogenase iron-molybdenum cofactor PF02579. This conserved domain belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB). However, its precise function is still undetermined [Ref]. Genome context analysis reveals (score 0.85) the presence of a ferredoxin protein (TM1815) in the vicinity of this target.
The SCOP database classifies 1t3v in the alpha/beta class, within the ribonuclease H fold, nitrogenase accesory factor-like superfamily, MTH1175-like family (SCOP53146). The crystal structure of the same protein is available (PDB:1o13). DALI top hits are with the PH0822 protein PDB:2yx6 (Z=15), MJ0327 protein PDB:2qtd (Z=13), and TA1041 protein PDB:2re2 (Z=12).
