| Title | Crystal structure of Activation (AdoMet binding) domain of Methionine synthase (TM0269) from Thermotoga maritima at 2.2 A resolution. To be published | | Site | JCSG | | PDB Id | | Target Id | 282146 | | Molecular Characteristics | | Source | Thermotoga maritima msb8 | | Alias Ids | TPS1196,TM0269 | Molecular Weight | 22889.11 Da. | | Residues | 202 | Isoelectric Point | 5.13 | | Sequence | mpkveiapseikipdnvlkaklgfggaeeipeefrktvnrayeelldaakpvvlwrdfevdgslsfddm rltgelatkhlsgskiitvflatlgkkvdekieeyfrkgedllaffidgiasemveyalrkvdaelrmk rsnlegsfrispgygdlplslnkkiaeifkeevdvnviedsyvlvprktitafvgwreknekqt | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.30 | Rfree | 0.29 | | Matthews' coefficent | 2.99 | Rfactor | 0.251 | | Waters | 103 | Solvent Content | 58.81 |
| Pathway | | Reactions found in Metabolic Reconstruction for TM0269 | Name: methionine synthase
Other genes that carryout this rxn: TM0268
Metabolic Subsystem: Methionine Metabolism
Reaction: :
5mthf
Name:5-Methyltetrahydrofolate
Formula:C20H24N7O6
KEGG:
C00440
+
hcys-L
Name:L-Homocysteine
Formula:C4H9NO2S
KEGG:
C00155
-->
h
Name:H+
Formula:H
KEGG:
C00080
+
met-L
Name:L-Methionine
Formula:C5H11NO2S
KEGG:
C00073
+
thf
Name:"5,6,7,8-Tetrahydrofolate"
Formula:C19H21N7O6
KEGG:
C00101
Classification: EC:2.1.1.13
|
| Ligand Information | | Ligands | | | Metals | | | |
Ligand Summary
References
