| Title | X-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease. Embo Rep. 4 704 2003 | | Site | ISPC | | PDB Id | | Target Id | W00186 | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | TPS11953,P04062 | Molecular Weight | 55575.49 Da. | | Residues | 497 | Isoelectric Point | 7.11 | | Sequence | arpcipksfgyssvvcvcnatycdsfdpptfpalgtfsryestrsgrrmelsmgpiqanhtgtgllltl qpeqkfqkvkgfggamtdaaalnilalsppaqnlllksyfseegigyniirvpmascdfsirtytyadt pddfqlhnfslpeedtklkiplihralqlaqrpvsllaspwtsptwlktngavngkgslkgqpgdiyhq twaryfvkfldayaehklqfwavtaenepsagllsgypfqclgftpehqrdfiardlgptlansthhnv rllmlddqrlllphwakvvltdpeaakyvhgiavhwyldflapakatlgethrlfpntmlfaseacvgs kfweqsvrlgswdrgmqyshsiitnllyhvvgwtdwnlalnpeggpnwvrnfvdspiivditkdtfykq pmfyhlghfskfipegsqrvglvasqkndldavalmhpdgsavvvvlnrsskdvpltikdpavgfleti spgysihtylwhrq | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.00 | Rfree | 0.230 | | Matthews' coefficent | 2.9 | Rfactor | 0.195 | | Waters | 938 | Solvent Content | 57.5 |
| Ligand Information | | Ligands | SO4 (SULFATE) x 15;NDG (2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE) x 1;NAG-NAG (N-ACETYL-D-GLUCOSAMINE) x 1 | | Metals | | | |
