TOPSAN > Proteins > CSGID > 3hzn

3hzn

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Table of contents

1. Protein Summary
2. Ligand Summary

Molecular Characteristics
Title	Structure of the Salmonella typhimurium nfnB dihydropteridine reductase. TO BE PUBLISHED
Site	CSGID
PDB Id	3hzn	Target Id	IDP00923
Source	Salmonella enterica subsp. enterica serovar typhimurium str. lt2
Alias Ids	TPS26348,99287, 16763955	Molecular Weight	23953.82 Da.
Residues	217	Isoelectric Point	5.40
Sequence	mdivsvalqrystkafdpskkltaeeadkiktllqyspsstnsqpwhfivasteegkarvaksaagnyt fnerkmldashvvvfcaktamddawlervvdqedadgrfatpeakaandkgrrffadmhrvslkddhqw makqvylnvgnfllgvaamgldavpiegfdaevldaefglkekgytslvvvpvghhsvedfnaglpksr lplettltev
	BLAST FFAS

Structure Determination
Method	XRAY	Chains	8
Resolution (Å)	2.40	Rfree	0.222
Matthews' coefficent	4.55	Rfactor	0.177
Waters	821	Solvent Content	72.99

Pathway
Reactions found in Metabolic Reconstruction for TM0578
Name: L-hydroxyproline reductase (NADP) Metabolic Subsystem: Proline Biosynthesis Reaction: : 1p3h5c Name:L-1-Pyrroline-3-hydroxy-5-carboxylate Formula:C5H6NO3 KEGG: C04281 + h Name:H+ Formula:H KEGG: C00080 + nadph Name:Nicotinamide adenine dinucleotide phosphate - reduced Formula:C21H26N7O17P3 KEGG: C00005 --> 4hpro-LT Name:trans-4-Hydroxy-L-proline Formula:C5H9NO3 KEGG: C01157 + nadp Name:Nicotinamide adenine dinucleotide phosphate Formula:C21H25N7O17P3 KEGG: C00006 Classification: EC:1.5.1.2
Name: pyrroline-5-carboxylase reductase (NADP) reversible Metabolic Subsystem: Proline Biosynthesis Reaction: : 1pyr5c Name:1-Pyrroline-5-carboxylate Formula:C5H6NO2 KEGG: C03912 + h Name:H+ Formula:H KEGG: C00080 + nadph Name:Nicotinamide adenine dinucleotide phosphate - reduced Formula:C21H26N7O17P3 KEGG: C00005 <==> nadp Name:Nicotinamide adenine dinucleotide phosphate Formula:C21H25N7O17P3 KEGG: C00006 + pro-L Name:L-Proline Formula:C5H9NO2 KEGG: C00148 Classification: EC:1.5.1.2

Ligand Information
Ligands	TLA (L(+)-TARTARIC) x 7;SIN (SUCCINIC) x 44;MLI (MALONATE) x 19;FLC (CITRATE) x 2;ACT (ACETATE) x 3
Metals	CL (CHLORIDE) x 12;NA (SODIUM) x 4

3hzn

Resources
- PDB
- PDBSum
- PSI-KB
- PlasmID
- Proteopedia
- GPSS
- ProFunc

Protein Summary

Ligand Summary

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