| Title | Structural and molecular mechanism for autoprocessing of MARTX toxin of Vibrio cholerae at multiple sites. J.Biol.Chem. 284 26557-26568 2009 | | Site | CSGID | | PDB Id | | Target Id | IDP00167 | | Molecular Characteristics | | Source | Vibrio cholerae o1 biovar el tor str. n16961 | | Alias Ids | TPS26732,243277, 4455065 | Molecular Weight | 483677.18 Da. | | Residues | 4545 | Isoelectric Point | 4.97 | | Sequence | mgkpfwrsveyfftgnysaddgnnnivaigfggqihayggddhvtvgsigatvytgsgndtvvggsayl kvedstghlivkgaagyadinksgdgnvsfagaaggvsidhlgnhgdvsyggaaayngitrkglsgnvt fagaggynalwhetnqgnlsftgagagnkldrtwsnryqgshgdvtfdgagaansissrvetgnitfrg agadnhlvrkgkvgditlqgagasnrierthqaedvytqtrgnirfegvggynslysdvahgdihfsgg gayntiirkgsgndfakegmtnakadeivltkavmsgswigqdhhvtavksasepntylfafadstytk inkvqlrndpqtgelkyystawykevnhlsnlanqdisdnggftavningaytlsdlkvehqqsvtvha vekslteyewvtyangavidakevslsdakmgghaiyadgtkvdvkavksnrqpntyiyakvlgpytki vvvelandpetgalkyqarswykegdhtanianqdissatgynpmgkggyslsdlhysvnavrstsetv adieeytdqtlfkpandsgessgdvrfngagggnviksnvtrgnvhfngggianvilhssqfgntefng ggaanvivksgeegdltfrgaglanvlvhqseqgkmdvyaggavnvlvrlgdgqylahllaygnisvqk gsgdsrvvmlggynthtqigsgnglwlaaggfnvmtqvgkgdvaavlagganvltkmgegeltsgmlgg anvithisnddqlsnttavalgganiltkkgkgntlavmggganvlthvgdgtttgvmvgganiltkvg ngdttgillgvgnvlthvgdgqtlgvmgaagniftkvgdgtsiavmigagnifthvgegnawalmgglg nvftkvgngdalalmvaeanvfthigdgmsvalmlakgnvatkvgngttlaamvgnvnifthighgstf aamigqanimtkvgndltaalmvgkanimthvgdgtslglfagevnvmtkvgngttlaamfgkanimth vgdgltgvlalgeanivtklgddfmgvvaaakanvvthvgdattaavlagkgniltkvgegttvgllis dvgnvmthvgdgttigiakgkanlitkvgdglgvnvtwgqanvftqvgdgdrynfakgeanlitkvgdg qevsvvqgeaniithvgngddytgawgkanvitkvghgqnvvlakgeanivtqvgdgdsfnalwskgni vtkvgdgmqvtaakgqanitttvgnglnvtaaygdanintkvgdgvsvnvawgkynintkvgdglnvav mkgkananihvgdglninasyaqnnvaikvgngdfyslavassntssnklsalfdnikqtvlgvggsqa inylvqgdeasssgthkgrgaiatpeitkldgfqmdaikevssdlgdsltgsvtkvdtpdlnkmqhaln vddssvqapnlivngdfelgehgwqsthgveasyagsvygvegeghgarvteldtytntslyqdlanla qgeviavsfdfakraglsnnegievlwngevvfsssxdesawqqknlkltaqagsnriefkgtghndgl gyildnvvatsessqqanairehatqnpaaqnalsdkeraeadrqrleqekqkqldavagsqsqlestd qqalenngqaqrdavkeeseavtaelaklaqgldvldgqathtgesgdqwrndfagglldgvqsqldda kqlandkiaaakqtlsdnnskvkesvakseagvaqgeqnragveqdiadaqadaekrkadalakgkdaq qaesdahhavnnaqsrgdrdvqlaenkanqaqadaqgakqnegdrpdrqgvtgsglsgnahsvegaget dshvntdsqtnadgrfseglteqeqealegatnavnrlqinagiraknsvssmtsmfsetnsksivvpt kvspeperqevtrrdvrisgvnleslsavqgsqptgqlasksvpgfkshfastsigienelsglvvvlp knsaqtfgyvhdsqgnplfmltkdmnqggysnpvgindiqgvnnwqthtielvtypseisdtaavesrk eamlwlakeftdhinqsnhqslphlvsddgrftlvisnskhliaagngtsidaqgktigmtpsgqqatm aisakefgtssspevrllesapwyqaglrdeflanaknttlddpataqnvyayltsvysktadlakeyg iyindwdpasegfspnaqgltdpkvknawsilprtkpvrmlellsaedsryvrqqiaeklkgtysesla knvfeyfqyggevaghginnattgsvqqpepailfefrsvpsalsdfvpktastvkvdvkaldhfdsas rkaiitevnalvsgsedfdawyqeyraskgqppvknpkssasanhkaewlmtqhaeqwakitapytdnh etltstklasndkeelhalgetsnlennkqqenvasiintmlndmlpfyalrternllvqegdegfevr awpgtedksktiiledpedaaqhkaierfilanfdnfeqmpdelflvdnkvishhegrthvlaqkvdga wqynatvelmsvtelldaanvtgkirgesyqqvidaltdyhasitehadyepesvekllnlrkkiegyv lghpdsgrveamnsllnqvntrldevsllsvaeqtiqaqnsfsrlydqleaanlkeskhlyldqngdfv tkgkgnlanidllgsreavlekvkltvsneygqtvadtifaglsakdlakdgkgvdiaglnkvhqaieq hlspvsatlyiwkpsdhsalghaalqigqgrtqlegqaaadfnqqnyvswwplgskssnisnilnvatk dqpdlklrwsdfsqpahqndtlehdvaseendgfglhdgdiklkrfieklnaakgidasfkeasegyas vllgnpdmlettsipahvfqpfveqwndtsydmmdvahrfaqelrlqaqrsddpellekrignvirqfa eraleeietfkasqadqgrvfrinlegldvaamqaewhrlsndpdaryqlltkncsstvakvlkaggad klightwlpkfgvwtptelfnfgqalqeaqleiaakkqshqvtdvldalsgnekpkenvaiendgtppr dkeslspltrflnnelygdkearrkigeitqtlldhavekgesqkitlqgeagrltgyyhqgtapsege tsspsgkvvlflhgsgssaeeqasairnhyqkqgidmlavnlrgygesdggpsekglyqdartmfnylv ndkgidpsniiihgysmggpiaadlaryaaqngqavsgllldrpmpsmtkaitahevanpagivgaiak avngqfsveknleglpketsillltdneglgnegeklrtkltasgynvtgeqtfygheasnrlmsqyad qivsglsssasvdedldqqgldttstkdqgisnkndhlqvvdskealadgkilhnqnvnswgpitvtpt tdggetrfdgqiivqmendpvvakaaanlagkhaessvvvqldsdgnyrvvygdpskldgklrwqlvgh grdhsetnntrlsgysadelavklakfqqsfnqaeninnkpdhisivgcslvsddkqkgfghqfinamd anglrvdvsvrsselavdeagrkhtkdangdwvqkaennkvslswdaqgevvakderirngiaegdidl srigvnnvdepargaigdnndvfdapekrkpetevianssssnqfsysgniqvnvgegeftavnwgtsn vgikvgtggfkslafgdnnvmvhigdgeskhsvdiggyqalegaqmflgnrnvsfnfghsndlilmmdk siptpplvnpfdgaarisgvlqgiatsgegedwlaaqeqqwtlsgakkfvkdmsgldqsssvdyttlve ldsqnerdsrglkhdaeatlnkqynqwlsgngnsgtsqlsradklrqaneklafnfavggqgadiqvtt gnwnfmfgdniqsildtnlgslfglmtqqftatgqakttftytpqdlprqlknkllgqlagvgaettla difgvdytasgqivsrngqavdgvailkemlevigefsgdqlqafvdpaklldslkagidmgadgiksf aethglkekapeeekdnssvsvnganvnsaqgatvadgntetaetqdrafgfnslnlpnlfatifsqdk qkemkslvenlkqnltadllnmkektfdflrnsghlqgdgdinislgnynfnwggdgkdlgaylgdnnn fwggrgddvfyatgksniftggegndmgvlmgrenmmfggdgndtavvagrinhvflgagddqsfvfge ggeidtgsgrdyvvtsgnfnrvdtgddqdysvtignnnqvelgagndfanifgnynrinagagndvvkl mgyhavlnggdgddhliataiskfsqfnggegrdlmvlggyqntfkggtdvdsfvvsgdvidnlvedir sednivfngidwqklwfersgydxklsilrdpsndsdqskfehigsvtfsdyfngnraqvvigmsekdlsgereytmlsdsaidalvqamsgfepqagdngfidslesksqaaismawsdvvhkkglmv | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 1.95 | Rfree | 0.21616 | | Matthews' coefficent | 2.06 | Rfactor | 0.16893 | | Waters | 321 | Solvent Content | 40.38 |
| Ligand Information | | Ligands | IHP (INOSITOL) x 2;UNX-UNX (UNKNOWN) x 2;UNX (UNKNOWN) x 8 | | Metals | CL (CHLORIDE) x 1 | | |
