| Title | A Specific Cholesterol Binding Site Is Established by the 2.8 A Structure of the Human beta(2)-Adrenergic Receptor. Structure 16 897-905 2008 | | Site | ATCG3D | | PDB Id | 3d4s | Target Id | ATCG3D_18 | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | P07550 | Molecular Weight | 55890.18 Da. | | Residues | 490 | Isoelectric Point | 8.90 | | Sequence | dykddddamgqpgngsafllapnrshapdhdvtqqrdevwvvgmgivmslivlaivfgnvlvitaiakfe rlqtvtnyfitslacadlvmglavvpfgaahilmkmwtfgnfwcefwtsidvlcvtasiwtlcviavdr yfaitspfkyqslltknkarviilmvwivsgltsflpiqmhwyrathqeaincyaeetccdfftnqaya iassivsfyvplvimvfvysrvfqeakrqlnifemlrideglrlkiykdtegyytigighlltkspsln aakseldkaigrntngvitkdeaeklfnqdvdaavrgilrnaklkpvydsldavrraalinmvfqmget gvagftnslrmlqqkrwdeaavnlaksrwynqtpnrakrvittfrtgtwdaykfclkehkalktlgiim gtftlcwlpffivnivhviqdnlirkevyillnwigyvnsgfnpliycrspdfriafqellclrrsslk hhhhhh | | | BLAST FFAS ProFunc GPSS |
| Structure Determination | | Method | XRAY | Chains | 1 | | Resolution (Å) | 2.80 | Rfree | 0.2725 | | Matthews' coefficent | 2.34 | Rfactor | 0.2300 | | Waters | 20 | Solvent Content | 47.36 |
| Ligand Information | | Ligands | TIM ((2S)-1-(TERT-BUTYLAMINO)-3-[(4-MORPHOLIN-4-YL-1,2,5-) x 1;CLR (CHOLESTEROL) x 2;OLC ((2R)-2,3-DIHYDROXYPROPYL) x 3 | | Metals | | | |
