| Title | DcpS as a therapeutic target for spinal muscular atrophy. Acs Chem.Biol. 3 711-722 2008 | | Site | ATCG3D | | PDB Id | | Target Id | ATCG3D_188 | | Molecular Characteristics | | Source | Homo sapiens | | Alias Ids | TPS24445,NP_054745 | Molecular Weight | 45953.79 Da. | | Residues | 397 | Isoelectric Point | 6.12 | | Sequence | mshhhhhhsgevkpevkpethinlkvsdgsseiffkikkttplrrlmeafakrqgkemdslrflydgir iqadqtpedldmedndiieahreqiggsapvrlpfsgfrlqkvlresardkiiflhgkvneasgdgdge davvilektpfqveqvaqlltgspelqlqfsndiystyhlfpprqlndvkttvvypatekhlqkylrqd lrliretgddyrnitlphlesqslsiqwvynildkkaeadrivfenpdpsdgfvlipdlkwnqqqlddl yliaichrrgirslrdltpehlpllrnilhqgqeailqryrmkgdhlrvylhylpsyyhlhvhftalgf eapgsgverahllaevienlecdprhyqqrtltfalraddpllkllqeaqqs | | | BLAST FFAS | | Structure Determination | | Method | XRAY | Chains | 2 | | Resolution (Å) | 2.31 | Rfree | 0.27605 | | Matthews' coefficent | 2.05 | Rfactor | 0.21071 | | Waters | 211 | Solvent Content | 39.88 |
| Ligand Information | | Ligands | DD1 (5-{[1-(2-FLUOROBENZYL)PIPERIDIN-4-) x 1 | | Metals | | | |
