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JCSG Highlight Stories
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| | Title | Author | Priority |
| 3s25:The protein structure reveals a 7-bladed propeller in which each blade is comprised of ~40 residues. This is a secreted protein. The structure is similar to that of WD40/YVTN repeat-like domains, whic... | debanu (8 edits) | |
| 3taw:Pfam Update: There is one other structure 1vkd, in that family, that is described thus in TOPSAN: Protein Summary The gene TM1225 from Thermotoga maritima encodes the NP_229030 protein from the DUF377... | haxelrod (5 edits) | |
| 3tzg:A porin-like solubile protein with unknown function. Only a couple of highly similar sequences, an orphan at this point. There are few more homologs in human metagenomics samples, but the most diverge... | adam (2 edits) qxu (2 edits) | |
| 3tdq:PilY2 is a representative of a small (~8 members), Psedomonas specific protein family, not classified in PFAM. Shown to be involved in fimbrial biogenesis, but its exact role appears to be unknown (se... | adam (3 edits) qxu (1 edits) | |
| 3u7z: RUMGNA_00854 protein matches to the "lid domain" of gastric intrinsic factor (2BB6 and 2PMV), according to FFAS and HHPRED. This structure was solved using 2BB6 as a search template, despite very low... | qxu (7 edits) adam (1 edits) | |
| 3rwx:Pfam Update: I have built this as Lipocalin_6, and it has 47 members , as PF13944. The other Lipocalins have structures. I have run jackhmmer on it and found 46 homologues, in uncharacterised Bacteroi... | haxelrod (11 edits) msedova (1 edits) | |
| 2lrg:BVU_3708 from Bacteroides vulgatus (target 393196) is a founding member of a new PFAM family DUF4425 (PF14466), which will be released as a part of PFAM 26.0 release (probably). BVU_3708 is a second ... | haxelrod (4 edits) adam (1 edits) | |
| Sestrin: Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress, as well as mediate p53 inhibition of cell growth by activating AM... | adam (2 edits) | |
| 3t2l:This structure is similar to previous JCSG structures 3gf8, 3liu, 3pay, 3r4r, 393142, likely involved in fimbrae formation. It demonstrate a novel form of oligomerization (dimer) through stand swappin... | qxu (12 edits) | |
| 3ufiSimilar to 3sy6 and 3t2l, belongs to the FimA superfamily.Ligand Summary | qxu (2 edits) |
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