PF09209

  

Resources
Pfam ID:	DUF1956	PDB:	1t33
Solved by:	MCSG	Priority Score:	3.6
Member of this family is in PDB.
Member of this clan is in PDB.
Co-occurence with annotated domain(s) (no restrictions on number of architectures).
HMMER:
# sequence matches: 300	# architectures: 4	# taxonomy ids:177
FFAS:
Top FFAS hit in PDB:	"1t33A, putative transcriptional repressor (TetR/AcrR"	Top FFAS hit in Pfam:	"PF08362, YcdC-like protein, C-terminal region "
GRDB:
Top significant hit (PDB90):	"1t33A, transcription ; structural genomics, the crystal structure of a putative transcriptional repressor (tetr/acrr family) from salmonella typhimurim lt2 "
Top significant hit (PFAM25U):	"PF08362, YcdC-like protein, C-terminal region"
CATH:	CATH Domain	E-value	CATH Node
	3himB00	0.0058
	2oi8A00	0.0068	1.10.357.10

Topsan Members

Summary

Pfam family PFAM:PF09209 {Domain of unknown function (DUF1956) } with 113 members in NR database and additional 26 members in the metagenomic datasets is represented in Bacteria. The first structural representative solved (PDB Id: TOPSAN:1t33) was subject to FATCAT structural similarity search that indicated similarity to SCOP (v. 1.73) domain SCOP:d1jt6a2 classified as Two domains: DNA/RNA-binding 3-helical bundle and Tetracyclin repressor-like, C-terminal domain fold. Profile-profile methods confirm remote homology between this family and superfamily of Tetracyclin repressor-like, C-terminal domain; fold of the same name. Based on remote homology confirmed by the structure one can hypothesize that this family is probably binds nucleic acids