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PF01937
Table of contents
- 1. Topsan Members
- 2. Summary
- 3. References
| Pfam Family | |
|---|---|
| Name: DUF89 | Accession: PF01937 (PFAM live) |
| Description | |
| Protein of unknown function DUF89 | |
| Comments | |
| This family has no known function. | |
Topsan Members
Tag pages as 'PF01937' to appear in this list.
| Name | Annotation | Author(s) |
1xfi
| ||
2g8l
| The PH1575 gene from Pyrococcus horikoshii encodes a protein of unknown function from the DUF89 group (PF01937). According to the SCOP classification, the 2g8l structure belongs to the class of multi... | pascual (2 edits) anton (1 edits) tinab (1 edits) |
2ffj
| The AF1104 (NP_069933.1) gene from Archaeoglobus fulgidus encodes a protein of unknown function DUF89 PF01937. The protein belongs to the class of multi-domain proteins (alpha and beta) and reveals A... | tinab (4 edits) anton (1 edits) pascual (1 edits) |
Summary
Pfam family PFAM:PF01937 {Protein of unknown function DUF89 } with 270 members in NR database and additional 42 members in the metagenomic datasets is represented in Archaea, Bacteria, and Eukaryota.
The first structural representative solved (PDB Id: TOPSAN:1xfi) was subject to FATCAT structural similarity search that yielded no results, thus suggesting that it is a novel fold. SCOP classifies 1xfi in the multi-domain protein class, AF1104-like fold. 1xfi coordinates show the chelation of a Mg ion by a conserved DN-/-/-D motif. DALI finds significant structural similarity of 1xfi only with 2g8l and 2ffj (Z=25).
In eukaryotes, the DUF89 is present fused with kinases and phosphatases. The sequence of the 1xfi structure from A. thaliana, NP_179324, is annotated as pantothenate kinase-related protein [Ref].
Reviews
References
